Abstract: Global warming is currently an important environmental issue. Based on the previous studies, climate change, characteristics of water resources, as well as water issues in China are introduced. Taking Yellow River as a case, the contribution of climate change to historical changes in runoff is preliminarily analyzed. According to the projected climate scenario and hypothetical scenario, the potential impacts of climate change on water resources, as well as sensitivity and vulnerability of water resources to climate change are studied. And adaptive strategies in water resources management to climate change are put forward based on the actual situation in China.