Abstract: The influences of the human body comfort on the daily life and work of the public are significant, and the studies of its changing characteristics are of great significance to the urban meteorological service. Based on the daily mean temperature, relative humidity and average wind speed data collected by 23 meteorological stations in Liaoning Province from 1964 to 2015, the human body comfort index is used to calculate the comfort index of the human body. The evolution of the comfort days of different grades in Liaoning Province is analyzed in accodance with the season scales. The optimal travel periods of the typical tourist cities are analyzed by using the rotation empirical orthogonal function decomposition method (REOF), and the analysis of the spatial variation in the geometric comfort index is carried out. An ArcGIS software is used to divide the comfort regions. The analysis results show that: ① The average number of the cold uncomfortable days in Liaoning Province has a decreasing trend, and the number of comfortable days has an increasing trend, meanwhile the number of days of the heat discomfort has a slight increase trend. The comfort degree is summer> autumn> spring> winter; ②Except for winter, the five typical tourist cities are suitable for tourism, the summer is the best season for tourists to have a great tour; Shenyang and Benxi are more suitable for the spring tourism, and Dalian city is more suitable for the autumn tourism; ③The changes of comfort in four seasons of Liaoning Province can be roughly divided into three regions: western Liaoning, Liaozhong and Liaodong. The specific situation varies with the seasons, and the overall comfort is gradually decreasing from the eastern to the western regions of Liaoning Province. The results given by this study are aimed to provide the theoretical suggestions and guiding opinions for the daily life and a scientific reference to the travel of the public.