Abstract: The Yangtze River, known as a "golden waterway", is the most important inland waterway in China. There are lots of ships in the waterway, many of which are in the mooring state due to loading or unloading and other reasons. After the impoundment of the Three Gorges project, the landslide occurs frequently in the reservoir area. The landslide-generated surge is likely to make the ship chain broken, which will cause seriours personal injury and property damage. At present, the main methods to study the force on the ship anchor chain are theoretical analysis and empirical analysis methods, while physical model tests are less used. Therefore, the discrepancy of the mooring force may appear betweeen the design situation and the actual situation. Based on the rock landslide physical model test, the researches on the mooring force change of the ships located in the river bend section and the straight segment near the landslide are carried out under different landslide conditions. The change law of the mooring forces near the bow and stern in the surge propagation process is obtained. And the change rules of ship mooring forces under different wave heights, different periods and different water depths are also got. Finally, the maximum mooring force calculation formula is deduced by using the multiple regression analysis method. The results can provide a reference for the safety management of ships in the Three Gorges Reservoir area.