Performance of lithium slag concrete is affected greatly by the reaction degree of lithium slag. For this reason, the reaction degree of lithium slag in cement-lithium slag is tested by HCl solution method. The pore structure of mortar at 3 d is tested by scanning electron microscope(SEM), and hydration products of pure cement mortar and cement-lithium slag at 1-3 d for each curing method are tested by energy-dispersive spectrometer(EDS). Four curing methods (standard curing, heat curing, alkali activated, and composite curing of alkali activated and heat curing) are presented, and their impacts on pore structure and hydration products are discussed. The research results suggest that reaction degree of lithium slag in lithium slag composite cement increases over time, which is lower in early hydration period, especially in 1-3 d. Different curing conditions have different promotion in lithium slag reaction degree. Relatively speaking, the effect of four curing conditions is in the order of composite curing> alkali excitation> heat curing> standard curing. Meanwhile, the incorporation of lithium slag or the change of curing condition will change the distribution of pore diameter, and can refine the pore structure and change the content of hydrated products in the paste. Therefore, the change of curing condition can promote the reaction degree of lithium slag and refine the microstructure of the paste.